Several genes known to be important for myeloid differentiation, including Pu.1, Id1, Cebpa, Csf2rb, Csf1r, Gfi1, Itgam, and Hoxa cluster genes were at least 2-fold upregulated in the NP23-NHD13 AML, using both assays (Supplementary Fig. S4). This evidence concerns the gene SPI1 and acute myeloid leukemia.