ITGAM and acute myeloid leukemia: To more clearly determine the origin of clonal Tcrb DJ rearrangements in the leukemic NP23-NHD13 mouse thymus, we euthanized two NP23/NHD13 mice with early AML (i.e, asymptomatic, but with increased WBC in peripheral blood), and sorted the thymic cells into Mac1+/Gr1+ and Mac1−/Gr1− populations (Supplementary Fig. S3C).