Thus, it is possible that high levels of LAT1 expression in surgical specimens would indicate the need to follow up the patient closely with frequent imaging in order to take precautions against recurrence and to start treatment as soon as possible Nevertheless, we have to admit that the number of the patients examined in this study is limited, and thus concrete establishment of LAT1 as an RCC prognostic biomarker should await further larger-scale investigations. Here, LAT is linked to renal cell carcinoma.