In this context, CD36 appeared as a promising candidate, considering previous indications of associations between CD36 rare loss-of-function coding mutations and impaired fatty acid metabolism, glucose intolerance, type 2 diabetes, arterial hypertension, atherosclerosis, cardiomyopathy and coronary heart disease in mice and humans11,16,22,23. Here, CD36 is linked to type 2 diabetes mellitus.