C-reactive protein (CRP), a marker of systemic inflammation, has been shown to be involved in crucial pathogenesis in a variety of negative health outcomes, including cardiovascular diseases,1 2 diabetes,3 cancer4 and cognitive decline.5 Since the value of CRP in the prediction of prognoses in health outcomes has been recognised, it is important, from a public health perspective, to identify people at risk of elevated CRP in an efficient and simple way. This evidence concerns the gene CRP and cardiovascular disorder.