Hierarchical clustering of patients according to the individual thigh muscles revealed that most patients with sarcoglycanopathies or LGMD2I can be distinguished from dystrophinopathies by muscle MRI according to the presence or absence of the concentric fatty infiltration pattern or trefoil with single fruit sign, indicating that these two distinctive patterns are of high differential value in distinguishing sarcoglycanopathies or FKRP-associated dystroglycanopathy from dystrophinopathies. The gene discussed is FKRP; the disease is autosomal recessive limb-girdle muscular dystrophy type 2I.