The distinctive patterns observed at the thigh level of DGC-related muscular dystrophies, including the trefoil with single fruit sign [13] and concentric fatty infiltration pattern [6], are highly specific for dystrophinopathies and FKRP-associated dystroglycanopathy, respectively. The gene discussed is FKRP; the disease is neuromuscular disease caused by qualitative or quantitative defects of dystrophin.