Interestingly, the hypermethylation status of these DSB-repair genes (XRCC3 and RAD51B) led to elevated PD-L1 expression, a result that is discordant with the aforementioned result of a hypermethylated MLH1 promoter in endometrial cancers by Sloan et al. [83]. The gene discussed is MLH1; the disease is endometrial cancer.