In addition, the percentage of Ki67+ cells and apoptotic cells (Fig. 6d-e) indicated that immunocyte mixtures treatment decreased the proliferation of tumour cells (Ki67-positive) and promoted apoptosis of tumour cells (TUNEL positive) in the PC-9 groups (PC-9PD-L1+ and PC-9PD-L1-). This evidence concerns the gene MKI67 and neoplasm.