IP-10 production from bronchial epithelial cells has been shown to correlate with asthma severity following rhinovirus infections [15] however a recent study using nasal cells from healthy showed increased IP-10 production following rhinovirus infection [17]; indicating that decreased IP-10 production in nasal cells may lead to increased risk for viral infection and spread to the lower airways. The gene discussed is CXCL10; the disease is viral infectious disease.