Moreover, a number of single nucleotide polymorphisms (SNPs) in association with neuroblastoma predisposition have been identified in genes recently, including TP53,19LIN28B,20HACE1,20LMO1,21BARD1,22NEFL23 and CDKN1B. 24 Moreover, a fine‐mapping analysis of BARD1 locus (2q35) also identified two independent genome‐wide neuroblastoma‐associated loci.25 However, the present identified genetic variations could not fully account for the carcinogenesis of neuroblastoma. This evidence concerns the gene TP53 and neuroblastoma.