BMAL1 and Merkel cell skin cancer: BMAL1 is a widely acknowledged transcriptional activator.19 To determine the transcriptional effects of BMAL1 on the development of MCC, we performed a genome‐wide RNA sequencing to acquire the transcriptional profile in mandibular condyles from 4‐, 6‐, 8‐ and 10‐week‐old Bmal1‐/‐ mice and the age‐matched wild‐type mice (Figure 4A).