Such antigen‐presenting cells that mediate CD8 T‐cell crosspriming (Sanchez‐Paulete et al, 2017) of tumor antigens are defective in BATF3−/− mice showing that they are required for a number of successful immunotherapies to work (Salmon et al, 2016; Sanchez‐Paulete et al, 2016; Spranger et al, 2017). This evidence concerns the gene CD8A and neoplasm.