Artemisinin and its derivatives, especially ART, are reported to play a role in the prevention or treatment of diabetes, mainly by inducing protective IL‐4‐producing T cells and regulatory T cells, suggesting that ART might inhibit cancer progression by reprogramming the metabolic profile of cancer cells.36 The present study showed that ART could decrease HMGCR protein levels and inhibit the MVA pathway. The gene discussed is HMGCR; the disease is cancer.