Four studies [47, 52, 66, 84] investigated the predictive effect of GH on subsequent MDD (total N = 118, median N = 29, MDD development n = 23, median N = 22, range for age [15–57], % female [52–100], follow-up time (0.5–9.6), QA score (4–8)), of which 2 investigated the same sample and one study that did not provide sufficient data for analysis [47]. Here, GH1 is linked to major depressive disorder.