Western blot analysis showed that GSK3β-S9A inhibited 30% OM-induced β-catenin upregulation without affecting p-PKCγ (Fig. 5f, Supplemental Fig. S5e), indicating that β-catenin upregulation in differentiated N2a is directly attributable to GSK3β inhibition. The gene discussed is GSK3B; the disease is ocular melanoma.