ABCA7 and Alzheimer disease: We found statistically significant associations for 6 markers located within intronic regions of 6 genes, including AC103796. 1-BDNF, PPP3R1, NGFR, KL, ABCA7 & CALHM1. Although functional studies are required to elucidate the role of these genes in the accumulation of Aβ and their potential implication in AD pathophysiology, our findings are consistent with results obtained in previous GWAS efforts.