Evidence of associations with previously established AD-specific loci include AC103796. 1-BDNF (rs2049048; p = 3.62e−04; OR, 0.45 [95% CI, 0.29–0.7]), PPP3R1 (rs7593613; p = 2.04e−03; OR, 1.59 [95% CI, 1.18–2.13]), NGFR (rs9908234; p = 2.45e−03; OR, 2.47 [95% CI, 1.38–4.43]), KL (rs648202; p = 2.90e−03; OR, 1.84 [95% CI, 1.23–2.75]), ABCA7 (rs3764650; p = 3.07e−03; OR, 2.01 [95% CI, 1.27–3.2]), CALHM1 (rs2986018; p = 4.16e−03; OR, 1.59 [95% CI, 1.16–2.18]), Table 2. The gene discussed is CALHM1; the disease is Alzheimer disease.