In the analyses of all participants adjusted for age (years), gender, smoking, number of APOE4 alleles and AD status, retinol (β = −1.436, 95% CI: −2.598 to −0.274, P = 0.02) and lutein (β = 0.041, 95% CI: 0.015 to 0.068, P = < 0.001) remained significantly associated with eGFR. This evidence concerns the gene APOE and Alzheimer disease.