Amounts of apoSOD/EDI-reactive SOD1 in the PD and PSP cases appeared not to be significantly dependent upon the presence and absence of the C4F6-reactive misfolded SOD1 (black filled circles in Fig. 6a and b); this would be partly because an amount of the misfolded SOD1 in PDSOD1/PSPSOD1 was much less than that of ALS (Fig. 4). The gene discussed is SOD1; the disease is Parkinson disease.