This association suggests that NGF [7, 43, 44] induces androgen overproduction in ovaries with PCOS, which is also a result of hyperactivation of the catecholaminergic system on ovarian steroid-secreting cells [32]; however, when the NGF actions were blocked in the ovaries, the ovarian functions are restored [46]. The gene discussed is NGF; the disease is polycystic ovary syndrome.