Three Cox-regression models were run as follows: without adjustment; adjusting for age, sex, and adjusting for age and sex as well as conventional clinical risk factors such as smoking, drinking, body mass index, hypertension, and diabetes; In the regression models, the ApoB/ApoA1 ratio was analyzed as categorical variables and the distributions of the ApoB/ApoA1 ratio among CHD subjects were divided into quartiles or tertils. The gene discussed is APOB; the disease is diabetes mellitus.