Indeed, many of the embryonic developmental genes were also found to be highly expressed in ovarian cancer compared to many other cancers in the TCGA data, including FOXL2, GATA4, NR5A1, AMHR2, MAL and WIPF3. Of these, the first three were further identified as potential upstream regulators that could explain the observed gene expression patterns. This evidence concerns the gene MAL and ovarian carcinoma.