Our results were also in accordance with the results obtained by Ng KL et al., in which they observed a significant upregulation in the expression of various pro-apoptotic proteins belonging to the Bcl-2 family, including Bax, in addition to an enhanced expression of the pro-survival protein Bcl-2 in K562 CML cells treated with γ-tocotrienol [3]. Here, BCL2 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.