Second, some experiments point at HFD subunits as direct “driver” oncogenes in specific types of cancers: NF-YB in diffuse large B-cell lymphoma (DLBCL), an aggressive evolution of follicular lymphoma [12]; NF-YC in choroid plexus carcinomas, as suggested by mouse/human synthenic screenings and functional analysis [13]. This evidence concerns the gene NFYB and diffuse large B-cell lymphoma.