ACHE and Alzheimer disease: Although the etiology of AD has not been fully elucidated yet, modern treatment strategies typically comprise anticholinesterases, including acetylcholinesterase (AChE) (EC 3.1.1.7) and butyrylcholinesterase (BChE) (EC 3.1.1.8); antioxidants; α, β, and γ secretase inhibitors; N-methyl-D-aspartate receptor agonists [24]; and inhibitors of the phosphorylation of AD-associated protein [25].