Therefore, based on this review, further experimental studies on the interplay between the AR-mediated miRNome regulation and the inhibition of adipogenesis are needed and also promising, especially in the light of the growing obesity epidemics and the well-known clinical effects of testosterone treatment on reducing adipose tissue in hypogonadal men [133,134]. The gene discussed is AR; the disease is obesity due to melanocortin 4 receptor deficiency.