Recently, Bian et al. observed that UCA1 induced 5-FU resistance in CRC cells via a ceRNA logic, whereby UCA1 inhibited miR-204-5p expression and its activity through competitively enriching miR-204-5p at its 3′UTR binding sequences, leading to the release of the mRNA of RAB22A and BCL2 [38]. The gene discussed is RAB22A; the disease is colorectal carcinoma.