For instance, lncRNA DQ786243 is the first reported lncRNA that participates in the pathogenesis of CD and CRC; ANRIL (also called CDKN2B-AS1) is dysregulated in an IBD pathology context and may regulate inflammatory responses by acting as a component of the nuclear factor-κB (NF-κB) pathway; the UC-associated lncRNA BC012900 represents its potential as a diagnostic biomarker in IBD progression since BC012900 is particularly differentially expressed in UC samples [88,89,90]. The gene discussed is NFKB1; the disease is inflammatory bowel disease.