CASP8 and breast cancer: Differently to the lncRNAs above that were correlated with EMT, the lncRNA in the non-homologous end-joining pathway 1 (LINP1) is overexpressed in drug-resistant cells and mediates its oncogenic role in BC by decreased apoptosis-related proteins (such as caspase-8 and caspase-9), thus promoting cell growth, metastasis, and chemotherapy resistance to 5-FU and DOX in BC [164].