Univariable Cox proportional hazard analysis showed that 17 risk factors were significantly associated with MACE, including MELD-XI score, age, male sex, great complexity of CHD, NYHA functional class ≥II,HCV antibody positivity, serum creatinine, eGFR, total bilirubin, GGT, AST, alanine aminotransferase (ALT), platelet count, SVEF<50%, SPV dysfunction, valvular disease, and pulmonary hypertension (Table 3). The gene discussed is GPT; the disease is pulmonary hypertension.