Overall, the cytokines profiles of NSCLC PE and plasma from CAR-T recipients were remarkably similar and dominated by sIL-6Rα, CCL2/MCP1, CXCL10/IP10, IL-6 and CXCL8/IL-8 (R = 0.80 and 0.77 compared to patients with CRS grades 0–3 and CRS 4–5, respectively). Here, CCL2 is linked to congenital rubella syndrome.