Collectively, we identified reduced infiltration of neutrophils and CD4 positive T lymphocytes in PtenΔ/ΔBRF1Tg prostate tumours, in keeping with reduced levels of immune/inflammatory response genes (Fig. 3a) and expression of Cd4 (RNA-Seq data: log2FoldChange = −1.8203; p.adj = 0.0067; Table S8) in prostate tumours from PtenΔ/ΔBRF1Tg mice. Here, CD4 is linked to prostate neoplasm.