CDH2 and hepatocellular carcinoma: Quantitative RT-PCR and western blot analysis showed no changes in the expression of epithelial (E-cadherin and zonula occludens-1) or mesenchymal (N-cadherin and vimentin) markers when H1HR was knocked down or overexpressed (Fig. 5a, b), suggesting that H1HR promotes the migration and invasion of HCC not through regulating the EMT.