CD79A and colitis: Such microbes include segmented filamentous bacteria (SFB),65 and Helicobacter species.32 Further, transfer of IgA-coated bacteria induced more severe colitis as compared to transfer of bacteria not coated with IgA.32 Thus, coating with T cell-dependent IgA seems to define preferentially members of the microbiota with enhanced inflammatory potential, and this is likely to play a major role in maintaining the intestinal ecosystem in a state conducive to fostering a diverse, healthy microbiota.