Western blot assays were further used to verify the role of TRIP13 in the migration and invasion of GBM cells, and the protein expression levels of β-catenin, N-cadherin and MMP7 were significantly reduced, while the expression of E-cadherin was increased, and these proteins are markers of migration and invasion, respectively (Fig. 3e). This evidence concerns the gene CDH2 and glioblastoma.