Multivariate analysis demonstrated that MTFR2 expression (HR, 1.96; 95% CI, 1.55-2.48; p=0.03) and lymph node metastasis (HR, 1.91; 95% CI, 1.43-2.56; p=0.02) were independent prognostic factors for OS (Table 2). The gene discussed is MTFR2; the disease is metastatic malignant neoplasm in the lymph nodes.