Decreased time spent in the open arms and decreased percentage of entries into the open arms, indicative of anxiety-like behavior, was also observed in AIE rats but was not modulated by Lsd1 siRNA and scrambled antagomir infusion into CeA (AIE+ Lsd1 siRNA/scrambled; p < 0.001 by Tukey’s post hoc test). Here, KDM1A is linked to Anxiety.