KDM1A and Anxiety: Interestingly, infusion with Lsd1 siRNA together with miR-137 antagomir in AIE rats (AIE+ miR-137 antagomir/Lsd1 siRNA) was able to block the miR-137 antagomir-mediated rescue of anxiety-like behaviors as indicated by decreased time spent in the open arms (p = 0.011 by Tukey’s post hoc test) and decreased percentage of entries into the open arms (p < 0.001 by Tukey’s post hoc test) compared to AIE+ miR-137 antagomir/control siRNA rats.