Wallerian-like degeneration has also been implicated in other PD models, with WLDS protecting after MPTP and 6-hydroxydopamine administration (Sajadi et al., 2004; Hasbani and O’Malley, 2006; Cheng and Burke, 2010), and with neuroprotection in Pink1 mutant flies by Highwire deficiency that can now be added to the list. This evidence concerns the gene PINK1 and Parkinson disease.