Many drugs have been explored in combination with Panobinostat in AML, such as Decitabine [84,85], AZA [86], BCL-2 inhibitor ABT-199 [87], Wee1 inhibitor MK-1175 [88], β-catenin antagonist BC2059 [89], LSD1 inhibitor SP2509 [90], BRD4 inhibitor JQ1 [91], FLT3 inhibitor AC220 [92], Bortezomib [93], CXCR4 antagonists [94], Doxorubicin [95], or DZnep [96]. This evidence concerns the gene BCL2 and acute myeloid leukemia.