NF1 and neoplasm: These murine models allowed a better comprehension of gliomagenesis: somatic Nf1 loss induced by Cre expression driven by different cell-specific promoters or induced by tamoxifen during embryogenesis, defined neural stem/progenitor cells (NPCs) and the more committed oligodendrocyte precursor cells (OPCs) as potential cell(s) of origin of OPG with latency of tumor development of 3 and 6 months, respectively [87,89,90].