Other cryptochrome gene variants have previously been shown to be associated with a decreased breast cancer risk including GT genotype of rs1056560 in CRY1 (OR = 0.84 95% CI = 0.71–0.99) and CC genotype of rs1401417 in CRY2 (OR = 0.24 95% CI = 0.08–0.73) in premenopausal women [37]. The gene discussed is CRY1; the disease is breast cancer.