CLOCK and breast cancer: Other epidemiological studies have indicated a negative effect of intronic rs3805151 [37], rs11932595, rs7698022, and 3′UTR SNPs rs1048004, rs1801260 [16] CLOCK polymorphism as well as a positive effect under the dominant genetic model of CLOCK rs6850524, rs13102385, rs11133391 on breast cancer susceptibility [34].