ERBB2 and neoplasm: As expected, variations could be detected for parameters that characterize the metastatic risk and the stage of the disease as well as human epidermal growth factor receptor 2 (HER2) status (p = 0.017), distant metastases, type of surgery, axillary node dissection, radiotherapy, number of previous systemic therapy lines, adjuvant treatment, neoadjuvant treatment (p < 0.001) and tumor size (p = 0.014) (Table 1).