Bearing in mind that mRNA measurements usually include cancer cells, normal cells, and tumor-associated stromal cells (and therefore they may be subjected to error [82, 86]) and that our studies as well as those of Yuan and Li [83] included only the small number of cases (104 vs. 60), it would be of interest to apply the IHC method to a large cohort of GC patients for a better assessment of a possible relationship between SATB1 and HER2. Here, SATB1 is linked to neoplasm.