The present research followed the modified HER2 immunoscoring system devised for gastric cancer by Hofmann et al. [35] as well as the current recommended testing algorithm, in which immunohistochemistry should be used as the initial testing method and FISH or silver in situ hybridization (SISH) should be employed to retest samples with an equivocal IHC (2+) score [36, 47, 49]. Here, ERBB2 is linked to gastric cancer.