Similarly, it was found that patients with female gender, HBsAg-negative, non-liver cirrhosis, Edmonson's histology grading 1-2, tumor number = 1, absence of microvascular or macrovascular invasion, or AST > ALT, “GG” genotype was significantly associated with shorter metastasis-free (Figure 3). This evidence concerns the gene GPT and cirrhosis of liver.