The matching factors such as age and sex between BLDs and NSCLC were considered in the following analyses, and finally the sex-and age-matched participants including 269 of NSCLC patients and 220 of BLDs patients were randomly divided into the training set including 56 of NSCLC and 56 of BLDs patients and the validation set including 213 of NSCLC and 164 of BLDs patients for DSHp-β N-glycosylation biomarker discovery. The gene discussed is SH2D1A; the disease is non-small cell lung carcinoma.