Variations c.-3275T > G, (TA)6>(TA)7, c.211G > A, and c.1091C > T within UGT1A1 as well as c.521T > C within SLCO1B1 are independent risk factors of mild unconjugated hyperbilirubinemia. This evidence concerns the gene UGT1A1 and Hyperbilirubinemia.