RUNX3 and colorectal carcinoma: Considering that low-grade dysplasia (LGD) is more closely associated with UC than with CRC, and LGD does not always progress to CRC, Garrity-Park et al. (2016) extended the scope of research to UC patients with LGD, and demonstrated critical roles of MINT1 and RUNX3 in the progression from LGD to CRC.