CD209 and cancer: Another approach to recruit natural DCs for cancer immunotherapy is to target DC subsets in vivo via specific receptors, e.g., DEC205, CLEC9A, and langerin to target cDC1s; CLEC4A4 to target cDC2; CLEC7A (dectin 1) to target cDC2 and MoDCs; CD209 (DC-SIGN), mannose receptor and macrophage galactose-type lectin to target macrophages, using antibodies to deliver antigens and activating agents (110–112).