At the acute phase (7 dpi), up-regulated genes were enriched in ribosome and DNA replication to activate host immune response (pathways of Toll-like receiver signal, Fc gamma R-mediated phagocytosis, Phagosome, and T cell receiver signaling) and defense against the pathogens via the pathways of measles, Epstein–Barr virus infection, herpes simplex infection, influenza A, leishmaniasis, pertussis, and S. aureus infection. The gene discussed is TLR4; the disease is measles.