At the last follow-up, patients were divided into 3 groups based on their acromegaly remission statuses after surgery: the remission group (26/64, 40.6%), the GH/IGF-1 discordant group (8/64, 12.5%), and the non-remission group (30/64, 46.9%). The gene discussed is IGF1; the disease is acromegaly.