The study, designed to investigate the potential neuroprotective effect of swimming training in a mouse model of PD induced by 6-OHDA (24), demonstrated that a 4-week-long training attenuated the following features associated with PD: increased number of falls in the rotarod test, impairment of long-term memory in the object recognition test, depressive-like behavior in the tail suspension test, and, at the same time, increase in ROS and IL-1β levels, inhibition of GPx activity, increase in GR and GST activities, and decrease in DA, HVA, and DOPAC levels. The gene discussed is IL1B; the disease is Parkinson disease.