Among the 111 anti-LGI1 encephalitis patients, 13 patients had ADs, including HT (n = 6), vitiligo (n = 2), anaphylactoid purpura (n = 1), SLE (n = 1), the coexistence of SLE and anaphylactoid purpura (n = 1), Sjögren's syndrome (SS) (n = 1), and uveitis (n = 1). This evidence concerns the gene LGI1 and systemic lupus erythematosus.