CAMK2A and Anxiety: Administering CNO to the C57BL/6J mice, the background strain, did not alter anxiety or despair-like behaviour, providing support to the evidence that the anxiolytic behavioural effects noted upon CNO administration to CamKIIα-tTA:TetO-hM3Dq mice are specific to hM3Dq DREADD-mediated activation of forebrain excitatory neurons.